BackgroundFluoropyrimidine with platinum-based chemotherapy has become the standard of care for advanced gastric and gastroesophageal (GEJ) cancer.Trials in colon cancer show that induction chemotherapy followed by maintenance chemotherapy is an efficacious strategy to maximize clinical response while minimizing toxicity.The current retrospective s

The estimation of the stability conditions, over-breaks, and spalling failures, which could inflict potential external dilution, is a key parameter so Bar Stool as to ensure the optimal design of the exploitation and its cost effectiveness The research undertaken aims at correlating established empirical approaches for the estimation of the stabili

Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging.Here, we show that TRIB2 is more abundant in naive CD4+ than CD8+ T cells and counteracts quiescence exit by suppressing AKT activation.TRIB2 deficiency increases AKT activity